亚洲av日韩一区二区,亚洲中文字幕久久无码精品,国产AV一区二区三区日韩,亚洲精品国产摄像头

您好,歡迎進(jìn)入研域(上海)化學(xué)試劑有限公司網(wǎng)站!
一鍵分享網(wǎng)站到:
  • 技術(shù)文章ARTICLE

    您當(dāng)前的位置:首頁 > 技術(shù)文章 > ELISA試劑盒絲氨酸/蘇氨酸蛋白激酶PIM3抗體分析

    ELISA試劑盒絲氨酸/蘇氨酸蛋白激酶PIM3抗體分析

    發(fā)布時(shí)間: 2014-04-24  點(diǎn)擊次數(shù): 996次

    ELISA試劑盒絲氨酸/蘇氨酸蛋白激酶PIM3抗體英文名稱  Anti-PIM3 
    中文名稱  絲氨酸/蘇氨酸蛋白激酶PIM3抗體 
    別    名  Kid 1; Kid-1; Kid1; Kinase induced by depolarization; ONCOGENE PIM 3; ONCOGENE PIM3; PIM 3; Pim 3 oncogene; PIM3; Pim3 oncogene; PIM3_HUMAN; Protein kinase Kid 1; Protein kinase Kid1; Serine/threonine kinase Pim 3; Serine/threonine kinase Pim3; Serine/threonine protein kinase Pim 3; Serine/threonine protein kinase Pim3; Serine/threonine-protein kinase Pim-3.  
    濃    度  1mg/1ml 
    規(guī) 格  0.2ml/200μg 
    抗體來源  Rabbit  
    克隆類型  polyclonal 
    交叉反應(yīng)  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig
    產(chǎn)品類型  一抗    
    ELISA試劑盒絲氨酸/蘇氨酸蛋白激酶PIM3抗體研究領(lǐng)域  腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶  
    蛋白分子量  predicted molecular weight: 36kDa 
    性    狀  Lyophilized or Liquid 
    免 疫 原  KLH conjugated synthetic peptide derived from human PIM3 
    亞    型  IgG 
    純化方法  affinity purified by Protein A 
    儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
    產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200 
    (石蠟切片需做抗原修復(fù)) 
     not yet tested in other applications.
     optimal dilutions/concentrations should be determined by the end user.  
    保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
    Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
    ELISA試劑盒絲氨酸/蘇氨酸蛋白激酶PIM3抗體產(chǎn)品介紹 The Pim family serine/threonine protein kinases were first identified in studies examining genes targeted for proviral insertion in murine leukemia virus-induced T lymphomas. Increased levels of Pim kinases predispose cells to lymphomagenesis and enhance the activity of mitogenic proteins such as p100, c-Myb, and Cdc2. In addition, Pim kinases are also involved in modulation of synaptic strength in neurons and anti-apoptotic signaling in hematopoietic progenitor cells. Pim-3, a member of the proto-oncogene Pim family that expresses serine/threonine kinase activity, shares significant homology with Pim-1 serine/threonine protein kinases. Pim-3 may function as a mediator of synaptic plasticity in the brain and is presumably involved in the anti-apoptosis process and cell cycle progression as well as the proliferation of human hepatoma cell lines. The Pim-3 protein is widely expressed, however no expression is observed in the colon, thymus, or small intestine.
    Function : Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
    Subunit : Interacts with BAD. Interacts with PPP2CA; this interaction promotes dephosphorylation of PIM3, ubiquitination and proteasomal degradation. Interacts with SOCS6 (By similarity).
    Subcellular Location : Cytoplasm.
    Tissue Specificity : Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus, liver, or small intestine. However, expression is augmented in premalignant and malignant lesions of these organs.
    Post-translational modifications : Ubiquitinated, leading to proteasomal degradation.
    Phosphorylated. Interaction with PPP2CA promotes dephosphorylation.
    Similarity : Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
    Contains 1 protein kinase domain.
    Database links : 
    UniProtKB/Swiss-Prot: Q86V86.3 
    Entrez Gene: 415116 Human 
    Entrez Gene: 223775 Mouse 
    Omim: 610580 Human 
    SwissProt: Q86V86 Human 
    SwissProt: P58750 Mouse 
    Unigene: 530381 Human 
    Unigene: Hs.530381 Human 
    Unigene: 400129 Mouse 

產(chǎn)品中心 Products
在線客服 聯(lián)系方式

服務(wù)熱線

021-54479081
021-54461587

国产一精品一aⅴ一免费| 午夜精品久久久久久| 午夜好爽好舒服免费视频| 日本欧美三级高清视频| 午夜影院一级片| 国产国产人免费人成免费视频| 亚洲综合色视频在线观看| 亚洲成AV人片在线播放无码漫画| .欧美激情久久| 日韩理论电影在线播放| 亚洲人成电影免费观看在线看| 免费全部高H视频无码| 主人拽奶头跪爬鞭打羞辱调教| 日本大尺度吃奶呻吟视频| 久久精品青草社区| 日韩黄色大片儿| 97影院午夜在线观看视频| 日本高清视频xxxxx| 国产成人综合野草| 国产精品成人观看视频国产奇米| 亚洲 欧美 日韩一区| 欧美日韩高清在线观看| 金瓶风月在线观看| 成人中文字幕一区二区三区| 特黄少妇60分钟在线观看播放| 蜜桃成熟时2初熟的蜜桃| 国产成人亚洲综合网色欲网久下载| 亚洲精品国产网红在线| 久久久久久久色| 西西免费大胆无码视频| 国产精品内射久久久久欢欢| 亚洲偷偷自拍| 欧美韩日精品一区| 99热精品久久只有精品黑人| 欧美高清一区二区三区| 中文字幕一区日韩在线视频| 久久国产乱子伦精品在| 年轻漂亮的人妻被公侵犯BD免费版| 浓毛老太交欧美老妇热爱乱| 午夜国产视频| 久久免视观看国产|